• Aktuell forskning & länkar

Insight in schizophrenia and risk of suicide: a systematic update

Javier D. López-Moríñigo, Ramón Ramos-Ríos, Anthony S. David & Rina Dutta.

Comprehensive Psychiatry. Volume 53, Issue 4, May 2012, Pages 313–322.

 

Abstract

Background

Suicide has been shown to represent the major single cause of premature death among patients with schizophrenia spectrum disorders. Insight has been proposed to increase such risk. However, this subject has not been sufficiently investigated, and inconclusive results have been reported.

 

Objective

The objective of this study is to systematically examine the role of insight in the risk of suicide attempts and completed suicide among patients with schizophrenia and related disorders.

 

Method

Articles assessing insight and suicidality in patients with schizophrenia spectrum disorders published between 1977 and 2010 were reviewed. A MEDLINE search strategy was used to identify studies using keywords. Application of meta-analytic techniques to selected studies was not possible because of important methodological differences between them.

 

Results

Fifteen studies met predetermined selection criteria. Ten failed to demonstrate a positive association between insight and risk for suicide.

 

Discussion

There is little evidence to support the suggestion that insight may represent a risk factor for suicide in patients with schizophrenia. If there is an association between such risk and insight, it appears to be mediated by other variables such as depression and, above all, hopelessness. Further studies with larger samples and longer follow-up periods in naturalistic conditions, in which insight should be evaluated from a multidimensional approach, are required to analyze this issue in depth, given the crucial implications that it may have on the development of a model for suicide prevention in schizophrenia.

Nyhetsarkiv

Länkar

Senaste nyheter